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Radix BioSolutions adopts Gyrolab xP workstation for immunoassay development.

Uppsala, Sweden, 27 April 2010

Gyros AB, a leader in the automation of miniaturized immunoassays, confirmed today that Radix BioSolutions, a US-based contract research organization specializing in custom assay development, reagent manufacturing, and a provider of assay services, will integrate a Gyrolab^™ xP workstation into their immunoassay development programs. Kerry Oliver, CEO at Radix Biosolutions explained the reasoning behind the decision, "The Gyros^™ platform enables us to develop immunoassays more rapidly than any other approaches currently available. At Radix we differentiate ourselves by fostering strong relationships with our customers by meeting project requirements and timelines, and always striving to exceed expectations. Our scientists provide the experience and capabilities in reagent definition and production, robust assay development and validation, and the regulatory compliance required during the development of a customer's therapeutic. It is essential for us to leverage leading edge technology at each stage of a project in order to best fulfill the unique needs of each customer."

Erik Walldén, CEO at Gyros, added: "We are extremely pleased that Radix BioSolutions have recognized one of the key benefits of our immunoassay platform, namely rapid assay development. We also believe that their unique approach of making identified assay reagents commercially available will enable other Gyrolab xP workstation users working in GLP environments in the USA to procure quality controlled reagents from Radix for their own laboratory needs."

AssayCheX™ Process Control Panel for Luminex/Bio-Plex Immunoassays

Learn how you can add a 4-plex Process control panel to any xMAP based immunoassay to evaluate every single well on your plate and save costs by reducing replicates and sample reruns. AssayChex gives you the power to:

• Verify individual data points
• Confirm assay performance
• Troubleshoot with greater ease
• Instantly flag potential failures
• Reduce the need for replicates

To place an order or for additional information, please call Gray Carr Bridgers at 512-869-8000 ext 115 or email her at gray@radixbiosolutions.com.

Radix BioSolutions and Indoor Biotechnologies Make Headlines

OCTOBER 14, 2009

Long-time strategic partners, Radix BioSolutions and Indoor Biotechnologies have been making significant strides in identifying indoor allergens that cause allergic diseases, including asthma, in millions of people. Now their partnership is also making headlines.

Featured in a recent article in the Wall Street Journal's Health section, Indoor Biotechnologies' breakthrough research into dangerous allergens has captured the attention of the scientific and healthcare communities. An essential component of their research is Radix BioSolutions' ability to customize Luminex xMAP^® multiplex assay technology.

Indoor Biotechnologies has been leveraging Radix's expertise in xMAP technology to develop and deliver custom assays that allow multiple allergens to be tested at the same time, in one sample and in low volumes. This ability has lead the collaboration to secure a major grant from the National Institute of Environmental Health Sciences (NIEHS), as well as accelerating the development of Indoor Biotechnologies' environmental tests for molds.

Now, the partners are using this advanced xMAP technology to conduct groundbreaking studies that will improve allergy diagnostic products and may one day lead to the development of immunotherapy for individuals suffering from severe allergies that are resistant to medications.

"Partnering with Radix BioSolutions provided the quality, consistency and reproducibility in custom bead conjugation that . . . allowed Indoor Biotechnologies to focus on validating this exciting new technology and getting it to market," explains Indoor Biotechnologies President Martin D. Chapman, PhD. "We have several projects in the pipeline and Radix BioSolutions is a key strategic partner in our product development operations."

• Read the Wall Street Journal article
• Learn more about Indoor Biotechnologies

Radix Sponsors Internet Café at Planet xMAP Amsterdam 2009

October 7-8, 2009

Radix BioSolutions is partnering with The MiraiBio Group of Hitachi Software in Amsterdam this October to introduce AssayCheX for immunoassays to the European market. This is Radix's second year sponsoring Planet xMAP in Amsterdam, and we're excited about the chance to sponsor the internet café. We always enjoy interacting with customers at conferences, but value Planet xMAP Europe as an incredible opportunity to engage leading minds on the future direction of Luminex xMAP Technology assay development and services. We look forward to seeing you there!

www.planetxmap.com

Radix BioSolutions Invited To Demonstrate the Power of Botulinum Toxin Multiplex Assay Panel

August 19-21, 2009

Radix BioSolutions Vice President of Research and Development Venkat Venkateswaran was honored to join a panel of researchers from academia, government agencies and the private sector invited to present at this year's Symposium and Workshop hosted by the Botulinum Research Center (BRC) at University of Massachusetts Dartmouth. This year's workshop focusing on the "Current Trends in Botulinum Toxin Detection" was held August 19-20 at Center's state-of-the-art research building located at the University of Massachusetts in Dartmouth. Through a series of workshops, seminars and presentations, researchers explored innovative ways to more effectively detect botulinum neurotoxins, which have potential to be used as biothreat agents.

Dr. Neeraja Venkateswaran, Research Scientist at Radix BioSolutions, gave a talk on "Fluorescent microsphere Array Multiplex botulinum toxin assay". Other presenters in the workshop included experts from US Food and Drug Administration Center for Food Security & Applied Nutrition, Centers for Disease Control, and New York State Department of Health. Modern botulinum detection methods were demonstrated to the workshop participants. Drs. Venkat Venkateswaran and Neeraja Venkateswaran performed a practical demonstration of multiplex detection of Botulinum toxin A,B,E&F using xMAP^® technology using BioPlex Suspension Array System.

In addition to being one of the organizers of the symposium's workshop which brings together leading minds in the field of toxin detection and defense, Dr. Venkat Venkateswaran also gave a presentation on "Fit-for-purpose botulinum assays" in the main Symposium on August 21, 2009.

"Understanding how botulinum toxins work, their applications and potential threats, is critical to developing defenses against them" explains Dr. Venkateswaran. "Radix BioSolutions is excited by the collaborative research to innovate the ways to detect these toxins with greater speed, accuracy and cost-efficiencies" Part of the research work was carried out by a Contract awarded to Radix Biosolutions in collaboration with Tetracore (Rockville, MD), Botulinum Research Center, University of Massachusetts Dartmouth (Dartmouth, MA), and Naval Research Laboratory (Washington, DC) by, United States Department of Homeland Security Science and Technology Directorate.

Radix BioSolutions Launches AssayCheX^™ and Collaboration with Hitachi Software

May 4-6,2009

Radix BioSolutions chose this year's Planet xMAP USA conference to announce the launch of its highly anticipated AssayCheX Process Control Panel, as well as its strategic distribution partnership with the MiraiBio Group of Hitachi Software.

Sharing a joint display at the event, MiraiBio and Radix BioSolutions demonstrated how AssayCheX, used in conjuncture with MiraiBio's powerful MasterPlex QT 4.0 software, significantly simplifies and accelerates the way data integrity is verified.

A 4-plex panel of process control mircospheres, AssayCheX is designed to ensure result integrity for every well of a Luminex xMAP immunoassay. Simple to use, AssayCheX eliminates the guesswork — improving data precision and efficiency by making it easy to identify and flag outliers.

Radix BioSolutions and MiraiBio received a tremendous response from attendees interested in the advantages offered by AssayCheX powered by MasterPlex QT 4.0. We believe the excitement we saw at Planet xMAP was just the beginning.

Radix Makes Science Work

October 8, 2008, Daily Planet

Radix Puts Customers First

Radix tackles a lot of challenging puzzles. The result is always a customized and highly specific product. "It's added value that our customers cannot get elsewhere."

The Vanguard of Luminex Technology

GEORGETOWN, TX — Radix BioSolutions mission is to effectively enable the scientific community to implement xMAP^® Technology to more efficiently attain their research and commercial goals. The company honors this commitment by developing quality laboratory solutions customized to meet customers' needs. This requires a market approach and customer interaction that is intimate and proactive. Vice President of Business Development and Marketing Erik Miller comments: "We put our customer first."

Radix BioSolutions was formed in 2001. Among the company's clientele are large pharmaceutical companies in the US and Europe, but also governmental parties such as the Centers for Disease Control (CDC), National Institutes of Health (NIH), and the National Cancer Institute. These customers are often in the need of a partner that can turn their specific expectations with the Luminex Technology into practical lab solutions. "Our customers often have applications that differ from the norm," says Miller. "We provide them with high quality, customized lab solutions. Radix has a unique capability to manage all of their specific and detailed needs."

Everything Radix does is custom, from development to production. Miller notes: "At Radix we focus on a solution that is designed precisely for our customers. Most of the time, they are doing something completely novel. Armed with our solutions, our customers are at the forefront of xMAP^® Technology applications."

To the benefit of customers

In order to meet all of their customer's requirements, Radix's processes remain flexible. This gives the customers confidence in the process. "First, we gather the product requirements and the customer agrees to the specifications before we start. We then develop the solution and confer with the customer on pinpointed decision moments. In this way, we engage the customer in the process and create routine interactions." Explains Miller.

The projects move forward very quickly and ultimately deliver a customer-specific product that meets the defined needs. "It's an added value that our customer's cannot get elsewhere. For example; We have a pharmaceutical customer who wants to run a six-plex cytokine assay. Three of these assays are commercially available. We determined the reagents for the three extra assays and we combined them with the commercial ones. We actually used assays from different vendors. We continually demonstrate that Radix operates to the benefit of customers, Luminex, and also the rest of the partner base. We don't look at the other Luminex partners as competition; they are our partners," boasts Miller.

Radix tackles a lot of challenging puzzles but also has a lot of fun, says Miller. "Radix is a very efficient Luminex-focused laboratory. Half of the employees have a Ph.D. degree. The others are scientists with expertise on the Luminex platform. There are only two of us not directly at the lab bench. That also shows how customer and technology-focussed we are."

Next level

According to Miller, Luminex fills a niche in the world of science. And Radix takes it to the next level. "Luminex operates in a very functional and pragmatic section of medicine. A focused set of markers are validated that may allow a clinician to get their arms around a complex problem. Basic research, by its nature, is often very new and novel. New assays and challenges need to be successfully engaged. Also, since there is this multitude of data points in a small sample, there is a lot of need to manage that amount of information. And that's where we come into the picture. Radix is considered to be the vanguard of the technology. And that, of course, is a big compliment to our scientists."

Radix is present at Planet xMAP to create awareness of its capabilities in the European market. "We absolutely believe that there is a need for someone like Radix in the European market. Apart from that, it is always interesting to so see what other people and partners are doing so that we can clearly visualize the forefront of Luminex Technology."