Capture Reagents: Our microsphere modification services are customized to your needs. You can choose the volume, the xMAP microsphere designation, and the capture reagent. We are not limited to single source reagent manufacturers, so we will bulk couple the reagent of your choice, without regard to its original source.
Alternative Functionalities: We also provide various chemical modifications that give you even more options for assay development and optimization. We have developed several alternative surface chemistries that can be used for more specific research needs. The choice of chemical modification depends on the functionality of your capture reagent. The following table classifies the capture reagents that can be used for different assay formats.
Alternatively Functionalized Beads
|Functionality||Complementary Functionality||Example Biomolecule||Application||Utility|
|Antibodies||Antigens||Proteins, peptides||Immunoassays, enzyme activity assays||Biomarker analysis and diagnosis|
|Antigens||Antibodies||Proteins, peptides||Immunoassays, enzyme activity assays||Diagnosis, serology, activity determination|
|Avidin — low capacity||Biotin-conjugated molecules||Proteins, peptides, Oligonucleotides||Immunoassays, nucleic acid assays, receptor ligand assays, enzyme
|Expression analysis, detection, diagnosis, peptide screening, synthetic or recombinant antibody screening|
|Avidin — high capacity||Biotin-conjugated molecules||Proteins, peptides, oligonucleotides||Immunoassays, nucleic acid assays, receptor ligand assays, enzyme activity assays||Expression analysis, detection, diagnosis, peptide screening, synthetic or recombinant antibody screening|
|Hydrazide||Carboxyl groups, aldehyde groups||Proteins, peptides, glycoproteins, carbohydrates||Immunoassays, receptor ligand assays||Peptide screening, synthetic or recombinant antibody screening|
|Maleimide||Sulfhydryl groups||Proteins, peptides||Immunoassays, receptor ligand assays||Peptide screening, synthetic or recombinant antibody screening|
|Antigen-specific antibody||Restricted availability antibodies||Immunoassays||Antibody screening, vaccine efficacy testing|
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